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SETTING THE PACE WITH
AVEIR™ LEADLESS
PACEMAKERS


The only leadless solutions that can provide therapy
for all common pacemaker indications1,2,3

AVEIR™ LEADLESS PACEMAKERS (LPs) ARE THE ONLY LEADLESS SOLUTIONS THAT CAN PROVIDE THERAPY FOR ALL COMMON PACEMAKER INDICATIONS1,2,3



AVEIR™ AR2 ATRIAL LEADLESS PACEMAKER (LP)
 

  • Sinus node dysfunction (SND) and normal atrioventricular (AV) and intraventricular conduction systems

Compare the clinical performance of AVEIR AR2 Atrial LP vs dual-chamber transvenous pacemakers

FIND OUT MORE ABOUT:

ARRIVE CLINICAL DATA


*Ventricular device providing AV synchrony based on the mechanical sensing of atrial activity. Device provides AV synchrony at rest and rate responsive (VVIR) pacing during periods of high patient activity.
† AAI(R)+VVI mode should not be used in patients without intact AV node conduction, or with chronic atrial fibrillation or atrial flutter.
AAI, atrial pacing; AAI(R), atrial pacing rate response; AF, atrial fibrillation; AV, atrioventricular; AVB, atrioventricular block; AVM, atrial management; DDD, dual-chamber pacing; DDD(R), dual-chamber pacing rate response; DR, double chamber; ESC, European Society of Cardiology; i2i, implant-to-implant; LP, leadless pacemaker; SND, sinus node dysfunction; TV, transvenous; VVI, single chamber ventricular pacing; VVIR, single chamber ventricular pacing rate response.

Upgradeable system1,6
The complete solution for SND patients

TAILORED THERAPY FOR SND PATIENTS


†AAI(R)+VVI mode should not be used in patients without intact AV node conduction, or with chronic atrial fibrillation or atrial flutter.
AAI(R), atrial pacing rate response; AF, atrial fibrillation; AR, atrial only; DDD(R), dual-chamber pacing rate response; DR, double chamber; i2i, implant-to-implant; SND, sinus node dysfunction; VR, ventricular device; VVI, single chamber ventricular

INTRODUCING AAI(R)+VVI†: PROGRAMMING THAT PROVIDES LONGEVITY AND FLEXIBILITY10,18



Atrial pacing rate response + single chamber ventricular [AAI(R)+VVI†] mode establishes two independently programmable devices (AVEIR™ AR2 Atrial LP and AVEIR™ VR Ventricular LP)

  • i2i™ communication is disabled, resulting in increased battery longevity for both devices
  • Program the atrial device for primary support and the ventricular device to a backup rate
  • Software update also includes increased pulse width programmability for better fine-tuning of pacing outputs

†AAI(R)+VVI mode should not be used in patients without intact AV node conduction, or with chronic atrial fibrillation or atrial flutter.

OVER 10 YEARS OF PROJECTED BATTERY LIFE FOR SND PATIENTS [AAI(R) AND AAI(R)+VVI†]1*

With AVEIR™ AR2 Atrial LP, Abbott advances leadless pacing therapy for better patient care.

  • AAI(R) & AAI(R)+VVI† modes: Up to 12.4 years battery life redefines the standard for leadless pacing for treating SND patients1
  • Dual-chamber DDD(R): ~8.6 years, comparable to transvenous pacemaker systems
MODE**ATRIAL PACINGPROJECTED ATRIAL DEVICE
LONGEVITY (YEARS)1
AAI(R), AAI(R)+VVI†100%12.4
DDD(R)***50%8.6

* AVEIR™ AR2 LP LSP203A: AAI(R) and AAI(R)+VVI† at 1.5 V, 300 ohms, 0.4 ms, 50 bpm, 100% atrial pacing.
** 1.5 V, 0.4 ms, 300 ohms, 50 bpm.
*** i2i™ setting = 4/4.
† AAI(R)+VVI mode should not be used in patients without intact AV node conduction, or with chronic atrial fibrillation or atrial flutter.
AAI(R), atrial pacing rate response; DDD(R), dual-chamber pacing rate response; VVI, single chamber ventricular.

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CONNECT TO THE LATEST
IN STRUCTURAL HEART
THERAPY

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AVEIR Atrial LP AAI Implant Med-in-a-Box: Step-by-Step Training Guide

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AVEIR DR Leadless Pacemaker Virtual Implant: Step-by-Step Guide

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Leadless Upgradability and Evolving Patient Needs with Prof. Tajstra

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Optimizing Tricuspid Valve Crossing Case 2 with Dr. Jacon

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Health Economics of Leadless Therapy with Prof. Vinolas Prat

Learn AVEIR Leadless Pacemaker Follow-Up Checks

Learn How to Perform Follow-Up Checks on the AVEIR Leadless Pacemaker

References
  1. AVEIR™ Leadless Pacemakers and Delivery Catheter IFU. ARTEN600361108.
  2. Micra‡ VR2 MC2VR01 IFU. 
  3. Micra‡ AV2 MC2AVR1 IFU. 
  4. Udo EO, Zuithoff NP, van Hemel NM, et al. Incidence and predictors of short- and long-term complications in pacemaker therapy: the FOLLOWPACE study. Heart Rhythm. 2012;9(5):728-35. doi: 10.1016/j.hrthm.2011.12.014.
  5. Cantillon DJ, Exner DV, Badie N, et al. Complications and Health Care Costs Associated With Transvenous Cardiac Pacemakers in a Nationwide Assessment. JACC Clin Electrophysiol. 2017;3(11):1296-1305. doi: 10.1016/j.jacep.2017.05.007.
  6. AVEIR Leadless Pacemakers and Delivery Catheter IFU. ARTEN600307044. ARTEN600350965.
  7. Cha YM, El-Chami MF, Liu CF, et al. 2026 HRS/AHA/APHRS/EHRA/IDSA/LAHRS/PACES/STS expert consensus statement update on cardiovascular implantable electronic device lead management and extraction. Heart Rhythm. 2026;S1547-5271(26)02264-2. doi: 10.1016/j.hrthm.2026.04.015.
  8. Boersma LV, El‑Chami M, Steinwender C, et al. Practical considerations, indications, and future perspectives for leadless and extravascular cardiac implantable electronic devices: a position paper by EHRA/HRS/LAHRS/APHRS. Europace. 2022;24(10):1691‑1708. doi:10.1093/europace/euac066.
  9. National Institute for Health and Care Excellence (NICE). Leadless cardiac pacemaker implantation for bradyarrhythmias. Health Technology Guidance HTG770. Feb 25, 2026. Accessed June 16, 2026. https://www.nice.org.uk/guidance/htg770.
  10. AVEIR Leadless Pacemakers and Delivery Catheter IFU. ARTEN600175957; ARTEN600307044; ARTEN600361109.
  11. Nilsson KR Jr, Birgersdotter-Green U, Saleem-Talib S, et al. Leadless atrial versus transvenous pacing for sinus node dysfunction: 1-year outcomes from the leadless ARRIVE real-world study. Europace. 2026;28(4):euag072. doi: 10.1093/europace/euag072.
  12. Ip JE, Brady PA, Kroman AM, et al. Leadless Versus Transvenous Single-Chamber Ventricular Pacemakers: Real-World Evidence From AVEIR™ VR Coverage With Evidence Development Study. J Am Heart Assoc. 2025;14(21):e042471. doi: 10.1161/JAHA. 125.042471.
  13. Lo M, Amin AK, Kowalski M, et al. Leadless Versus Transvenous Dual-Chamber Pacemakers: Real-World Evidence From AVEIR DR Coverage With Evidence Development Study. J Cardiovasc Electrophysiol. 2026;37(3):544-553. doi: 10.1111/jce.70255.
  14. Neuzil P, Exner DV, Knops RE, et al. Worldwide Chronic Retrieval Experience of Helix-Fixation Leadless Cardiac Pacemakers. J Am Coll Cardiol. 2025;85(11):1111-1120. doi: 10.1016/j.jacc.2024.10.094.
  15. Glikson M, Nielsen JC, Kronborg MB, et al. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J. 2021;42(35):3427-3520. doi: 10.1093/eurheartj/ehab364. Erratum in: Eur Heart J. 2022 May 1;43(17):1651. doi: 10.1093/eurheartj/ehac075.
  16. Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society. J Am Coll Cardiol. 2019;74(7):932-987. doi: 10.1016/j.jacc.2018.10.043. Erratum in: J Am Coll Cardiol. 2019;74(7):1014-1016. doi: 10.1016/j.jacc.2019.06.046. 
  17. Breeman KTN, Dijkshoorn LA, Wilde AAM, et al. Predicted Need for Atrial and Ventricular Pacing Per Indication Group in Patients With Dual-Chamber Pacemakers. Heart Lung Circ. 2023;32(5):629-637. doi: 10.1016/j.hlc.2023.02.007. Erratum in: Heart Lung Circ. 2024;33(2):e17. doi: 10.1016/j.hlc.2024.01.003.
  18. Ip JE, Cheung JW , Liu CF , et al. Maximizing battery longevity of leadless pacemaker systems by optimizing individualized programming. Heart Rhythm. 2026;23(2):e293-e294. doi: 10.1016/j.hrthm.2025.10.021.
  19. Vogt ML, Kellmann T, Ihara Z. Patient’s lifetime budget impact of a leadless pacemaker compared to transvenous pacemakers in France. Poster presented at: European Heart Rhythm Association; April 12-14, 2026; Paris.

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