Designed to treat patients with non-valvular atrial fibrillation (AF), who are at risk of ischemic stroke, the Amplatzer™ Amulet™ LAA Occluder offers complete closure of the left atrial appendage (LAA) and immediately eliminates the need for oral anticoagulants (OACs).1
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What is LAAO?
Left atrial appendage occlusion (LAAO) is a minimally invasive catheter-based therapy to close the left atrial appendage. The Amplatzer™ Amulet™ LAA Occluder provides complete closure, immediately eliminating the need for OACs.
For those patients who are either contraindicated for OACs or wish to discontinue use, LAAO is a viable option to reduce their risk of stroke.
Reducing stroke risk
David Hildick-Smith, MD, Royal Sussex County Hospital, Brighton, England
“What this therapy [use of the Amplatzer™ Amulet™ LAA Occluder] does for the patient is twofold. One, it physically deals with the problem and reduces the risk of stroke very substantially. But more than that, it also offers patients a peace of mind.”
The Amplatzer™ Portfolio App helps physicians determine which Amplatzer Structural Interventions device to use by suggesting applicable devices based on respective Instructions for Use.
ESOC 2023: LAAO case
LAAO Summit 2023: Complications
LAAO Summit 2023: Successful implant
LAAO Summit 2023: Live case 1
LAAO Summit 2023: LAA anatomies
LAAO Summit 2023: Anatomy & imaging – Panel
LAAO Summit 2023: Anatomy & imaging – The future
LAAO Summit 2023: CT
LAAO Summit 2023: LAAO therapies
LAAO Summit 2023: The clinical reality
- Amplatzer™ Amulet™ LAA Occluder Instructions for Use.
- Lakkireddy D, Thaler D, Ellis CR, et al. Amplatzer™ Amulet™ Left Atrial Appendage Occluder versus Watchman™ device for stroke prophylaxis (Amulet IDE): A randomized, controlled trial. Circulation. 2021; 144(19) :1543–1552. doi.org/10.1161/CIRCULATIONAHA.121.057063.
- Suradi HS, Hijazi ZM. Left atrial appendage closure: outcomes and challenges. Neth Heart J. 2017;25:143–151. doi.org/10.1007/s12471-016-0929-0.
- Kakkar AK, Mueller I, Bassand J-P, et al. Risk profiles and antithrombotic treatment of patients newly diagnosed with atrial fibrillation at risk of stroke: perspectives from the international, observational, prospective GARFIELD registry. PLoS ONE. 2013; 8(5):e63479. doi.org/10.1371/journal.pone.0063479.
- Baman JR, Mansour M, Heist EK, et al. Percutaneous left atrial appendage occlusion in the prevention of stroke in atrial fibrillation: a systematic review. Heart Failure Rev. 2018;23:191–208. doi.org/10.1007/s10741-018-9681-4.
- European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery; Camm AJ, Kirchhof P, Lip GY, et al. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010;31(19):2369–429. doi.org/10.1093/eurheartj/ehq278. Erratum in: Eur Heart J. 2011;32(9):1172. PMID: 20802247.