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ULTIPACE™PACING LEAD
CONDUCTION SYSTEM PACING



DISCOVER THE CLINICAL EVIDENCE

Explore Kevin Vernooy’s insights on conduction system pacing.

DEMONSTRATED LEFT BUNDLE BRANCH AREA PACING (LBBAP) SUCCESS AND SAFETY

*Composite success rate of acceptable capture thresholds and sense amplitudes for LBBAP at 6 months post-implant.

EXPLORE THE CLINICAL COMPENDIUM

Real-world evidence

STUDY OVERVIEW2

  • Study design: Retrospective, observational real-world evidence (RWE) study 
  • Data sources: Medicare Insurance Claims and Abbott Device Registry 
  • Study population: 2,341 LBBAP vs 68,241 right ventricular pacing (RVP) patients that received de novo dual chamber pacemakers
  • Leads studied: Abbott Tendril™ STS and UltiPace™
  • Follow-up: 2 years

RESULTS2
SAFETY OUTCOMES2

  • No difference in rates of 30-day acute complications
  • No difference in chronic complications
  • No difference in re-intervention rates at two-year follow-up
    • LBBAP had significantly lower rate of upgrades to cardiac resynchronization therapy (CRT) vs RVP

LBBAP BY STYLET-DRIVEN LEADS SIGNIFICANTLY REDUCED RISKS OF:

  • Heart failure hospitalization (HFH): 28%
  • New onset of HFH: 46%
  • All-cause mortality: 36%

WITH SIMILAR RATES OF:

  • 30-day complications HR 1.01, [0.82-1.24]
  • Chronic complications HR 0.92, [0.73-1.17]
  • Device reinterventions HR 0.76, [0.58-1.02]

vs RVP at 24-month follow-up
 

DOWNLOAD THE RWE PUBLICATION FLYER

High success rate with CPS Locator™ 3D catheters

Implantation of a stylet-driven lead for left bundle branch area pacing guided by new delivery catheters3
STUDY OVERVIEW:

  • Two-center study aiming to report the first clinical experience of LBBAP using a stylet-driven lead and new delivery catheters
  • Implant procedural data collected from 27 patients who received LBBAP implants using stylet-driven leads (Tendril™ STS) guided by CPS Locator™ 3D catheters
  • Lead implant location adjudicated based on fluoroscopy and paced QRS morphology 

RESULTS2

  • LBBAP implant successful in 100% of patients, with a single attempt in 81% of the patients and 2 attempts for the remaining
  • Time from venous access to lead fixation: 17 ± 15 mins
  • No LBBAP implant related procedural complications

CONCLUSION:

  • LBBAP using the stylet-driven leads guided by CPS Locator™ 3D catheters was safe and effective with a high success rate
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References
  1. Vijayaraman P, Foo D, Lim TSE, Diamantakos E, Verma S, Hourdain J, Pandurangi U, Bhargava K, Zanon F, Stone J, Lee K, Nair D. Result of the left bundle branch area pacing data collection registry, an international multicenter study of conduction system pacing with a Tendril STS 2088 stylet-driven lead. J Cardiovasc Electrophysiol. 2024 Jul;35(7):1452- 1460.
  2. Vijayaraman P, Sharma PS, Atwater BD, et al. Two-year follow-up of the safety and clinical outcomes of stylet-driven leads for left bundle branch area pacing compared with right ventricular pacing in the Medicare population. Heart Rhythm. 2026 Jan;23(1):169-179. doi: 10.1016/j.hrthm.2025.07.004.
  3. Nair D, Atwater B. Implantation of a stylet-driven lead for left bundle branch area pacing guided by new delivery catheters: A two-center experience. J Arrhythmia. 2023; 39:13-268. AB-752-CIED-CRT. Available at: doi.org/10.1002/joa3.12902. Accessed June 2026.

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