EDGE-TO-EDGE REPAIR (TEER)
MitraClip™ is the first minimally invasive TEER* therapy that delivers a life-changing treatment option for selected patients with Primary Mitral Regurgitation (PMR) or Secondary Mitral Regurgitation (SMR) who would otherwise go untreated.1,2 MitraClip™ is the standard of care in TMVr built on proven mitral valve therapy with over 20 years of experience, an extensive body of clinical evidence, and more than 200,000 patients treated worldwide.3
CONTROL MEETS EFFICIENCY
MITRACLIP™ G5
G5 is the next evolution of the MitraClip™ Transcatheter Edge-to-Edge-Repair (TEER) System* offering easy handling, precise positioning, and intuitive deployment that enhances both control and efficiency, allowing you to focus on what matters most—you patients
EASY HANDLING
- Quick, secure docking with spring-loaded attachments for easy connection
- Precise locking with binary lock knob to support consistent performance
- Built-in fastener for easy securement of the DC
PRECISE POSITIONING
- New guide attachment with braking system maintains desired positioning for enhanced control
- Controlled movement with redesigned stabilizer rail and handles
- Responsive new handle design capable of delivering 1:1 rotation
INTUITIVE DEPLOYMENT
- New lock knob offers easy and straightforward lock line release and removal
- Hard stop within arm positioner reduces dependence on visual indicators for more control
- Disconnect with ease using new release pin with finger hold to initiate deployment
MITRACLIP™ IMPLANTS
A BROAD RANGE OF SIZES FOR TAILORED TREATMENT ACROSS A WIDE RANGE OF COMPLEX ANATOMIES14
Explore the expanded portfolio of clip sizes and help more of your patients enjoy a quality of life they never thought possible.
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*The testimonial does not provide any indication, guide, warranty or guarantee as to the response patients may have to the treatment or effectiveness of the product or therapy in discussion. Opinions about the treatment discussed can and do vary and are specific to the individual’s experience and might not be representative of others.
**Tests performed by and data on file at Abbott.
- MitraClip™ G4 System Instructions for Use.
- Lim DS, Reynolds MR, Feldman T, et al. Improved functional status and quality of life in prohibitive surgical risk patients with degenerative mitral regurgitation after the transcatheter mitral valve repair. J Am Coll Cardiol. 2014;64(2):182–192. doi.org/10.1016/j.jacc.2013.10.021.
- Data on file at Abbott.
- Heidenreich PA, Bozkurt B, Allen LA, et al. “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association. Joint Committee on Clinical Practice Guidelines.” J Am Coll Cardiol. 2022;28(5):E1–E167. doi.org/10.1016/j.cardfail.2022.02.010.
- Mirabel M, Lung B, Baron G, et al. What are the characteristics of patients with severe, symptomatic, mitral regurgitation who are denied surgery? Eur Heart J. 2007;28(11):1358–1365. doi.org/10.1093/eurheartj/ehm001.
- Cioffi G, Tarantini L, De Feo S, et al. Functional mitral regurgitation predicts 1-year mortality in elderly patients with systolic chronic heart failure. Eur J Heart Fail. 2005;7(7):1112–1117. doi.org/10.1016/j.ejheart.2005.01.016.
- Rottbauer WD. Contemporary Clinical Outcomes with MitraClip™ (NTR/XTR) System: Core-lab Echo Results from +1000 Patient the Global EXPAND Study. Data presented at PCR 2020.
- Maisano F. Clip Selection Strategy and Outcomes with MitraClip™ (NTR/XTR): Evidence-Based Recommendations from the Global EXPAND Study. Data presented at PCR 2020.
- Rodriguez E. Contemporary Outcomes with the MitraClip™ G4 System: Preliminary Results based on the EXPAND G4 Study. Data presented at TCT 2021.
- Vahanian A, Beyersdorf F, Praz F, et al. ESC/EACTS Scientific Document Group, 2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), Eur Heart J.2022;43(7):561–632, doi.org/10.1093/eurheartj/ehab395.
- Yeo KK, Tan JWC, Muller DW, et al. Asian Pacific Society of Cardiology Consensus Recommendations on the Use of MitraClip for Mitral Regurgitation. Eur Cardiol. 2021;16:e25. doi.org/10.15420/ecr.2021.01.
- McDonagh TA, Metra M, Adamo M, et al., ESC Scientific Document Group, 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC, Eur Heart J.2012; 42(36):3599–3726, doi.org/10.1093/eurheartj/ehab368.
- Stone G, et al. Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation, N Engl J Med 2023; 388;2037-2048. Feldman T. et al. Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation: 5-Year Results of EVEREST II. JACC. December 2015; 66(25):2844-2854. Nickenig G. et al. Percutaneous edge-to-edge repair for tricuspid regurgitation: 3-year outcomes from the TRILUMINATE trial. JACC. 2024 September 23; 17(18):2113-2122
- Maisano F. Clip Selection Strategy with 4th Generation MitraClip™: Evidence-Based Recommendations from the Global EXPAND Study. Data presented at PCR London Valves 2022.